About Maharashtra Public Service Commission: Maharashtra Public Service Commission (MPSC) is a Constitutional Body established Under Article 315 of the Constitution of India which provides a smooth and efficient functioning of the Government of Maharashtra by providing suitable candidates for various Government posts and advising them on various service matters like formulation of Recruitment Rules, advise on promotions, transfers, and disciplinary actions, etc.
Maharashtra Public Service Commission – Assistant Commissioner Group-B Under Public Health Department
|Subject & No. of Marks||Medium of Exam||No. of Questions, Marks||Duration||Level||Nature of Paper|
|Respective disciplines||English||100 (200 marks)||1 Hour||Graduation Degree||Objective Type|
Physiology, Pathophysiology, Pharmacology, and Toxicology:
Physiology – i) Composition/ function of Blood elements, ii) Coagulation of blood, iii) Blood groups, iv) Blood components, manufacturing, v) Whole human blood (I.P.), vi) Blood bank- operation/requirements.
Pathophysiology- STD, AIDS, Hypersensitivity, HBsAg
Pharmacology – Factors modifying drug action, drugs affecting coagulation. Antihypertensive drugs, Antipyretic, Analgesic, Antitussive, Sedative, Hypnotics, Opioids, NSAIDS, Local Anaesthetics, Chemotherapeutic Agents including Anticancer drugs, Antifungal Agents, Drugs affecting CNS, Antidiabetic drugs, Contraceptive drugs, Hormones, Drugs acting on the uterus.
Toxicology – Classification of poison, chelating agent, heavy metals, and antidotes.
Sterilization procedure, Aseptic technics, disinfections, pyrogens, LAL Test, Assay of antibiotics/vitamins, biochemical serological, virological technics, BOD, different media, microbial drugs, drug resistance, microbial limit test, pathogenic organism of common occurrence.
Biochemistry & Chemistry of Drugs/Pharmaceuticals:
3.1 DNA, RNA, Nucleic Acid & components, enzymes, metabolism of protein, carbohydrate, lipids, recombinant technology and its application, immunological product-vaccine, sera.
3.2 Isomers, Tautomers, fermentation, synthesis of antibiotics, diazo reaction, the chemistry of steroids 3.3 Dosage forms, sustained release, dosage form, enteric coating, new drugs, parental drugs, Good manufacturing practices, Good laboratory practices, Routes of administration, Preservatives, suspending / emulsifying agents. Types of vehicles/types of waters, storage conditions for pharmaceuticals.
3.4 Principal and application of analysis, UV spectra / I.R./HPLC /GLC / Atomic absorption, HPTLC, LCMS, limit test, heavy metals, devices, and sutures.
3.5 Surgical – Medical devices sutures
3.6 Law -DCC, DTAB, Misbranded, standard, spurious, adulterated drugs definitions, Government Analyst duties, Inspector – power/procedure, definition schedule M/Y/ U
General Knowledge related to Pharmaceuticals / Medicine field:
01) National Health Programme,
02) DPCO / NPPA,
03) Narcotic Drugs,
04) Poisons – Antidotes,
05) Essential Drugs,
06) Central Drug Authority
08) Magic Remedies – Act and Rules,
09) Import of Drugs and Cosmetics,
10) Central Drug Laboratory,
11) WHO – GMP – identification,
12) Current events.
13) Consumer Protection Act,
14) Right to Information Act.
Questions will be asked to test how far candidates can think quickly and accurately
Maharashtra Public Service Commission (MPSC),
51/2, 7 and 8th Floor,
Cooperage Telephone Exchange Building
Maharshi Karve Marg,
Cooperage, Mumbai – 400021.
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